The Professional Advisory Board of The Marfan Foundation is in agreement with the Expert Consensus Document on the Treatment of Descending Thoracic Aortic Disease Using Endo-Vascular Stent-Grafts (Ann Thorac Surg 2008;85:S1-41) and the American Heart Association (AHA) guidelines entitled “Surgical Management of Descending Thoracic Aortic Disease: Open and Endovascular Approaches” (Circulation 2010; 121:1544–79) which indicate that stent-grafts are contraindicated in patients with Marfan syndrome and related connective tissue disorders.